SCHEMBL594164

SCHEMBL594164

CCOC(=O)C(C)(C)C1CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.39
CYP4A11 Q02928 3/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
PKM P14618 3/20 0.35
THRB P10828 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.34
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
MMP8 P22894 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2865658 0.98 CYP4F2 (0.38) CYP4F2CYP4A11MEN1KMT2ASLC6A2
SCHEMBL22680074 0.90 PKM (0.39) CYP4F2CYP4A11MEN1KMT2ASLC6A2
SCHEMBL22680072 0.90 PKM (0.39) CYP4F2CYP4A11MEN1KMT2ASLC6A2
Hydrochloric Acid SCHEMBL22491839 0.88 PKM (0.41) CYP4F2CYP4A11MEN1KMT2ASLC6A2
Hydrochloric Acid SCHEMBL22655521 0.88 PKM (0.41) CYP4F2CYP4A11MEN1KMT2ASLC6A2
SCHEMBL15910254 0.86 CYP4F2 (0.39) CYP4F2CYP4A11MEN1KMT2ASLC6A2
SCHEMBL19071938 0.81 ALDH1A1 (0.41) CYP4F2CYP4A11MEN1KMT2ATHRB
SCHEMBL25453903 0.81 SLC6A2 (0.37) CYP4F2CYP4A11MEN1KMT2ASLC6A2
SCHEMBL1226998 0.80 SLC6A1 (0.36) CYP4F2CYP4A11MEN1KMT2ASLC6A2
SCHEMBL15361076 0.80 CYP4F2 (0.36) CYP4F2CYP4A11MEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503436-B2 Compounds and compositions for treating conditions associated with STING activity NOVARTIS PHARMA AG (CH) 2025-12-23 US disclosed
US-20250059157-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2025-02-20 US disclosed
US-20240424111-A1 Degrader Compounds and Uses Thereof CALICO LIFE SCIENCES LLC (US) 2024-12-26 US disclosed
EP-4384503-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM Due, Inc. (US) 2024-06-19 EP disclosed
CN-118119595-A Compounds and compositions for the treatment of diseases associated with STING activity 艾福姆德尤股份有限公司 2024-05-31 CN disclosed
EP-4359409-A1 DEGRADER COMPOUNDS AND USES THEREOF Calico Life Sciences LLC (US) 2024-05-01 EP disclosed
US-20230303514-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2023-09-28 US disclosed
US-20230303514-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2023-09-28 US disclosed
US-20230303514-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2023-09-28 US disclosed
US-20230167057-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-06-01 US disclosed
US-20080269288-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2008-10-30 US disclosed
US-20080269288-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2008-10-30 US disclosed
WO-2008053194-A2 PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS ASTRAZENECA AB (SE) 2008-05-08 WO disclosed
EP-1854793-A1 NOVEL AMINOPYRIDINE COMPOUND WITH Syk INHIBITORY ACTIVITY Japan Tobacco, Inc. (JP) 2007-11-14 EP disclosed
US-20070167428-A1 Thienopyrroles as antagonists of gnrh ASTRAZENECA AB (SE) 2007-07-19 US disclosed
US-20070167428-A1 Thienopyrroles as antagonists of gnrh ASTRAZENECA AB (SE) 2007-07-19 US disclosed
US-20060205731-A1 Novel aminopyridine compounds having Syk inhibitory activity JAPAN TOBACCO INC. (JP) 2006-09-14 US disclosed
WO-2004080952-A1 PHENYLSULFONAMIDE DERIVATIVES FOR TREATING ALZHEIMER'S DISEASE BAYER HEALTHCARE AG (DE) 2004-09-23 WO disclosed
WO-2004080952-A1 PHENYLSULFONAMIDE DERIVATIVES FOR TREATING ALZHEIMER'S DISEASE BAYER HEALTHCARE AG (DE) 2004-09-23 WO disclosed
US-5614534-A Derivatives of β, β-dimethyl-4-piperidineethanamine as inhibitors of the cholesterol biosynthesis FOURNIER INDUSTRIE ET SANTE (FR) 1997-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303514-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 CYP4F2 1930/4885CYP4A11 828/4885MEN1 4517/4885
US-20080269288-A1 CHEMICAL COMPOUNDS HSD11B1, CYP11B1, CYP4A11 CYP4F2 40/4885CYP4A11 3/4885MEN1 1083/4885
US-20240424111-A1 Degrader Compounds and Uses Thereof PTPN1, PTPN2, PTPN5 CYP4F2 1297/4885CYP4A11 1550/4885MEN1 2212/4885
US-12503436-B2 Compounds and compositions for treating conditions associated with STING activity STING1, CGAS, IRF3 CYP4F2 4760/4885CYP4A11 3911/4885MEN1 2199/4885
US-20070167428-A1 Thienopyrroles as antagonists of gnrh GNRHR, PRLHR, TRHR CYP4F2 732/4885CYP4A11 812/4885MEN1 923/4885
US-20060205731-A1 Novel aminopyridine compounds having Syk inhibitory activity SYK, BTK, ZAP70 CYP4F2 3699/4885CYP4A11 3889/4885MEN1 4612/4885
US-20250059157-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 CYP4F2 1930/4885CYP4A11 828/4885MEN1 4517/4885
US-20230167057-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 CYP4F2 4760/4885CYP4A11 3911/4885MEN1 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.