SCHEMBL5951823

SCHEMBL5951823

CCCC/C=C/[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 2/20 0.41
F3 P13726 2/20 0.41
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
FAAH O00519 3/20 0.37
TRPV1 Q8NER1 1/20 0.37
PPARG P37231 4/20 0.37
TERT O14746 3/20 0.37
PTPN1 P18031 3/20 0.37
PPARD Q03181 3/20 0.37
PPARA Q07869 3/20 0.37
TOP1 P11387 3/20 0.37
MAPT P10636 2/20 0.37
BLM P54132 2/20 0.37
HSD17B10 Q99714 2/20 0.37
FABP4 P15090 2/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5951829 1.00 F7 (0.41) F7F3TSHRALDH1A1FAAH
SCHEMBL11122649 0.90 FAAH (0.50) F7F3FAAHTRPV1PPARG
SCHEMBL18270282 0.90 FAAH (0.50) F7F3FAAHTRPV1PPARG
SCHEMBL11122653 0.90 FAAH (0.50) F7F3FAAHTRPV1PPARG
SCHEMBL18270292 0.90 FAAH (0.50) F7F3FAAHTRPV1PPARG
SCHEMBL28723430 0.85 TERT (0.31) F7F3FAAHTRPV1PPARG
SCHEMBL28240702 0.85
SCHEMBL5853081 0.82
SCHEMBL5853083 0.82
SCHEMBL25861862 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114341215-B Curable composition 株式会社日本触媒 2024-12-27 CN disclosed
EP-3805282-B1 METHOD FOR PRODUCING VINYL-ETHER-GROUP-CONTAINING (METH)ACRYLIC ACID ESTER POLYMER, VINYL-ETHER-GROUP-CONTAINING (METH)ACRYLIC ACID ESTER POLYMER, AND POLYMER COMPOSITION NIPPON CATALYTIC CHEM IND (JP) 2024-09-11 EP disclosed
US-11780961-B2 Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof ZHEJIANG UNIVERSITY (CN) 2023-10-10 US disclosed
CN-112218901-B Vinyl ether group-containing (meth) acrylate polymer, process for producing the same, and polymer composition 株式会社日本触媒 2023-08-25 CN disclosed
US-11643490-B2 Method for producing vinyl-ether-group-containing (meth)acrylic acid ester polymer, vinyl-ether-group-containing (meth)acrylic acid ester polymer, and polymer composition NIPPON SHOKUBAI CO., LTD. (JP) 2023-05-09 US disclosed
CN-114341215-A Curable composition 株式会社日本触媒 2022-04-12 CN disclosed
US-20210246245-A1 METHOD FOR PRODUCING VINYL-ETHER-GROUP-CONTAINING (METH)ACRYLIC ACID ESTER POLYMER, VINYL-ETHER-GROUP-CONTAINING (METH)ACRYLIC ACID ESTER POLYMER, AND POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2021-08-12 US disclosed
EP-3805282-A1 METHOD FOR PRODUCING VINYL-ETHER-GROUP-CONTAINING (METH)ACRYLIC ACID ESTER POLYMER, VINYL-ETHER-GROUP-CONTAINING (METH)ACRYLIC ACID ESTER POLYMER, AND POLYMER COMPOSITION Nippon Shokubai Co., Ltd. (JP) 2021-04-14 EP disclosed
WO-2021039801-A1 CURABLE COMPOSITION 株式会社日本触媒 2021-03-04 WO disclosed
WO-2021039799-A1 CURABLE COMPOSITION 株式会社日本触媒 2021-03-04 WO disclosed
CN-112218901-A Method for producing vinyl ether group-containing (meth) acrylate polymer, and polymer composition 株式会社日本触媒 2021-01-12 CN disclosed
US-7038070-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2006-05-02 US disclosed
US-6963017-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2005-11-08 US disclosed
EP-0968158-B1 METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM BASELL POLYOLEFINE GMBH (DE) 2005-08-10 EP disclosed
US-20050033076-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2005-02-10 US disclosed
US-20030009046-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780961-B2 Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof DUOX1, SOD1, DUOX2 F7 785/4885F3 839/4885TSHR 4669/4885
US-20050033076-A1 Preparation of preparing substituted indanones CYP1A2, CYP2J2, IDH3A F7 416/4885F3 494/4885TSHR 4624/4885
US-20030009046-A1 Preparation of preparing substituted indanones CYP1A2, CYP1B1, CYP1A1 F7 422/4885F3 484/4885TSHR 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.