Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955047 | 0.88 | KMT2A (0.56) | SMN1; SMN2MEN1KMT2ACYP3A4POLB | |
| SCHEMBL5955275 | 0.88 | KMT2A (0.56) | SMN1; SMN2MEN1KMT2ACYP3A4POLB | |
| SCHEMBL5955265 | 0.83 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL5954427 | 0.80 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2APOLBGAA | |
| SCHEMBL5955007 | 0.79 | MEN1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL5955129 | 0.77 | PLCG1 (0.55) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL1685398 | 0.76 | KMT2A (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5954554 | 0.76 | LTA4H (0.50) | ALDH1A1MEN1KMT2ALTA4HTSHR | |
| SCHEMBL5955299 | 0.76 | LTA4H (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL6167967 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025589-A1 | 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes | LABORATOIRES FOURNIER S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025589-A1 | 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes | LIPC, CYP4F2, SLC5A2 | SMN1; SMN2 4641/4885ALDH1A1 452/4885MEN1 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.