Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169375 | 0.84 | GAA (0.50) | ALDH1A1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL6169699 | 0.77 | GAA (0.49) | ALDH1A1ALOX12NPSR1GAACYP3A4 | |
| SCHEMBL5954554 | 0.75 | LTA4H (0.50) | ALDH1A1MEN1KMT2ATSHRLTA4H | |
| SCHEMBL5954399 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2ATSHRLTA4H | |
| SCHEMBL6167361 | 0.74 | GAA (0.58) | ALDH1A1ALOX12NPSR1MEN1KMT2A | |
| SCHEMBL6168233 | 0.72 | NPC1 (0.48) | ALDH1A1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL13879473 | 0.71 | NR1H3 (0.51) | ALDH1A1NPSR1MEN1KMT2ATSHR | |
| SCHEMBL5955299 | 0.71 | LTA4H (0.50) | ALDH1A1MEN1KMT2ATSHRLTA4H | |
| SCHEMBL8726537 | 0.70 | MEN1 (0.60) | ALDH1A1NPSR1MEN1KMT2ATSHR | |
| SCHEMBL6169513 | 0.70 | L3MBTL1 (0.48) | ALDH1A1MEN1KMT2AGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |