Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.48 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.48 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907452 | 0.86 | HDAC1 (0.50) | HDAC1KDM1APLOD2PLOD3PLOD1 | |
| SCHEMBL5956512 | 0.79 | TGFBR1 (0.59) | TGFBR1HPGDSRAB9ANPC1 | |
| SCHEMBL5956548 | 0.79 | HDAC1 (0.48) | HDAC1KDM1APLOD2PLOD3PLOD1 | |
| SCHEMBL29932837 | 0.78 | JAK2 (0.60) | HDAC1KDM1APLOD2PLOD3PLOD1 | |
| SCHEMBL5956425 | 0.75 | HPGD (0.52) | TGFBR1RAB9AALDH1A1HPGD | |
| SCHEMBL6960733 | 0.74 | SCN10A (0.53) | RAB9AKDM4CNPC1MAPTKDM4E | |
| SCHEMBL5907501 | 0.73 | HDAC1 (0.47) | HDAC1KDM1ATGFBR1RAB9ANPC1 | |
| SCHEMBL4388206 | 0.72 | JAK2 (0.70) | HDAC1JAK2 | |
| SCHEMBL11633917 | 0.72 | RAB9A (0.66) | RAB9ANPC1MAPTKDM4E | |
| SCHEMBL32256 | 0.71 | MTOR (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | HDAC1 1234/4885KDM1A 2586/4885PLOD2 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.