Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790926 | 0.86 | HDAC1 (0.46) | HDAC1KDM1AMAPTNPC1RAB9A | |
| SCHEMBL6181106 | 0.81 | WNT3A (0.48) | KMT2ALMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL6181580 | 0.79 | WNT3A (0.45) | HDAC1KDM1ANPC1RAB9AMEN1 | |
| SCHEMBL6182297 | 0.79 | TGFBR1 (0.44) | NPC1RAB9AMEN1KMT2ATGFBR1 | |
| SCHEMBL6182682 | 0.79 | MAP4K4 (0.47) | NPC1RAB9AKMT2ATGFBR1LMNA | |
| SCHEMBL5956434 | 0.79 | HDAC1 (0.53) | HDAC1KDM1AMAPTNPC1RAB9A | |
| SCHEMBL6179073 | 0.78 | TLR7 (0.47) | MAPTNPC1RAB9APKMMEN1 | |
| SCHEMBL6180198 | 0.77 | TGFBR1 (0.47) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL6184116 | 0.77 | TRPV1 (0.48) | HDAC1KDM1AMEN1KMT2ATGFBR1 | |
| SCHEMBL6180356 | 0.77 | RAB9A (0.48) | HDAC1KDM1AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730049-A1 | COSMETIC PORTION | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-12-13 | — | — | EP | disclosed |
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | DODIC NERINA | 2005-11-03 | — | — | US | disclosed |
| WO-2005085089-A1 | COSMETIC PORTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | SMAD2, SMAD3, ALK | HDAC1 1275/4885KDM1A 1516/4885MAPT 1496/4885 |
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | HDAC1 1234/4885KDM1A 2586/4885MAPT 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.