Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790926 | 0.89 | HDAC1 (0.46) | WNT3ACHRNA7CHRNA10CHRNA9HDAC1 | |
| SCHEMBL5956493 | 0.81 | HDAC1 (0.46) | HDAC1 | |
| SCHEMBL5956662 | 0.79 | LOXL2 (0.55) | WNT3ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5956490 | 0.79 | WNT3A (0.39) | WNT3AHDAC1KDM1A | |
| SCHEMBL5956496 | 0.79 | HPGD (0.50) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5956509 | 0.78 | IRAK4 (0.41) | WNT3AMAPT | |
| SCHEMBL5956440 | 0.78 | WNT3A (0.43) | WNT3AHDAC1NPC1RAB9AMAPT | |
| SCHEMBL5956502 | 0.78 | PRKAB2 (0.47) | HDAC1HTTKDM1A | |
| SCHEMBL5956453 | 0.77 | TGFBR1 (0.45) | WNT3A | |
| SCHEMBL26354203 | 0.77 | RAD52 (0.48) | WNT3ACHRNA7HDAC1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-05 | — | — | US | disclosed |
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
| EP-1554275-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-20 | — | — | EP | disclosed |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | disclosed |
| WO-2004013134-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | BET1, VRK1, VRK2 | WNT3A 4013/4885CHRNA7 3748/4885CHRNA10 4140/4885 |
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | WNT3A 787/4885CHRNA7 2545/4885CHRNA10 2595/4885 |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | PGGT1B, BET1, CYP51A1 | WNT3A 4049/4885CHRNA7 3918/4885CHRNA10 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.