Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.70 |
| ▸ | CCR5 | P51681 | 1/20 | 0.70 |
| ▸ | CCR8 | P51685 | 1/20 | 0.70 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | BCR | P11274 | 4/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463685 | 1.00 | CCR1 (0.70) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL31695263 | 0.95 | CCR1 (0.76) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL27344644 | 0.95 | CCR1 (0.76) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL17406767 | 0.85 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL842265 | 0.85 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL5956691 | 0.85 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL2190158 | 0.85 | CYP2A6 (0.62) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL6183900 | 0.85 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL17051592 | 0.85 | CYP2A6 (0.57) | CCR1CCR5CCR8CYP2A6UHRF1 | |
| SCHEMBL842170 | 0.84 | CYP2A6 (0.67) | CCR1CCR5CCR8CYP2A6UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034027-A1 | METHOD FOR PREPARING GLASS NANOSTRUCTURES AND NANOSTRUCTURED SUBSTRATES THEREOF | CORNING INCORPORATED | 2025-01-30 | — | — | US | disclosed |
| US-12022832-B2 | Compounds and methods for treating nematode infections | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-07-02 | — | — | US | disclosed |
| US-20240074301-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-02-29 | — | — | US | disclosed |
| US-11864458-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230345812-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230331757-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230320188-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-05 | — | — | US | disclosed |
| US-20230309396-A1 | Host Materials for Electroluminscent Devices | UNIVERSAL DISPLAY CORPORATION | 2023-09-28 | — | — | US | disclosed |
| US-20230287011-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-09-14 | — | — | US | disclosed |
| CN-112552353-A | Iridium metal complex and organic photoelectric element using same | 浙江华显光电科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-10224491-B2 | Amine-based compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-03-05 | — | — | US | disclosed |
| US-10208026-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-02-19 | — | — | US | disclosed |
| US-9957441-B2 | Amine-based compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-05-01 | — | — | US | disclosed |
| WO-2017076187-A1 | 1,4(1,4)-DIPHENYLHEXACYCLOPHANE-12,43-DIYL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2017-05-11 | — | — | WO | disclosed |
| US-20150266863-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150266863-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-24 | — | — | US | disclosed |
| US-20040087623-A1 | Pyrazole derivatives against tgf overexpression | GLAXO GROUP LIMITED (GB) | 2004-05-06 | — | — | US | disclosed |
| EP-1355903-A1 | PYRAZOLE DERIVATIVES AGAINST TGF OVEREXPRESSION | GLAXO GROUP LIMITED (GB) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002066462-A1 | PYRAZOLE DERIVATIVES AGAINST TGF OVEREXPRESSION | GLAXO GROUP LIMITED (GB) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12022832-B2 | Compounds and methods for treating nematode infections | HNMT, NISCH, HRH2 | CCR1 1016/4885CCR5 1571/4885CCR8 1321/4885 |
| US-20230309396-A1 | Host Materials for Electroluminscent Devices | CRHR1, CRHR2, CRH | CCR1 27/4885CCR5 158/4885CCR8 6/4885 |
| US-20230345812-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OPRD1, OCIAD2 | CCR1 563/4885CCR5 1162/4885CCR8 2173/4885 |
| US-10224491-B2 | Amine-based compound and organic light-emitting device including the same | AOC2, TYR, TAAR1 | CCR1 2658/4885CCR5 3158/4885CCR8 4038/4885 |
| US-20230320188-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, MLX | CCR1 802/4885CCR5 1443/4885CCR8 1729/4885 |
| US-20230287011-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD2, OXGR1, OCIAD1 | CCR1 3163/4885CCR5 1891/4885CCR8 2473/4885 |
| US-11864458-B2 | Organic electroluminescent materials and devices | RAP1A, L1CAM, SOD1 | CCR1 1295/4885CCR5 3216/4885CCR8 2677/4885 |
| US-20240074301-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ICOSLG, OCIAD2, OSBP | CCR1 2004/4885CCR5 786/4885CCR8 869/4885 |
| US-10208026-B2 | Organic electroluminescent materials and devices | ZYX, LBR, LOXL1 | CCR1 1816/4885CCR5 2572/4885CCR8 549/4885 |
| US-20040087623-A1 | Pyrazole derivatives against tgf overexpression | TGFBR1, SMAD3, TGFBR2 | CCR1 824/4885CCR5 1748/4885CCR8 2395/4885 |
| US-20230331757-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD2, SSB, L1CAM | CCR1 744/4885CCR5 1474/4885CCR8 1782/4885 |
| US-20150266863-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ZYX, LBR, LOXL1 | CCR1 1816/4885CCR5 2572/4885CCR8 549/4885 |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OPRD1, L1CAM, OPRM1 | CCR1 1427/4885CCR5 1275/4885CCR8 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.