Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 13/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5957632 | 0.85 | TRPA1 (1.00) | TRPA1 | |
| Hydrochloric Acid SCHEMBL5957410 | 0.85 | TRPA1 (0.77) | TRPA1 | |
| SCHEMBL5957457 | 0.84 | TRPA1 (0.79) | TRPA1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5957548 | 0.82 | TRPA1 (0.98) | TRPA1HPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL5957690 | 0.82 | TRPA1 (1.00) | TRPA1ALDH1A1 | |
| SCHEMBL5957784 | 0.82 | TRPA1 (1.00) | TRPA1ALDH1A1 | |
| SCHEMBL5957359 | 0.82 | TRPA1 (1.00) | TRPA1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5957821 | 0.81 | TRPA1 (0.77) | TRPA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5957611 | 0.81 | TRPA1 (0.98) | TRPA1ALDH1A1 | |
| SCHEMBL5957636 | 0.81 | TRPA1 (1.00) | TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY | 2006-02-23 | — | — | US | claimed |
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | MMP13, MMP25, MMP15 | TRPA1 3405/4885HPGD 208/4885TSHR 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.