SCHEMBL5959613

SCHEMBL5959613

Nc1ccc(C#Cc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.75
CASP3 P42574 1/20 0.64
SENP8 Q96LD8 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
SENP6 Q9GZR1 1/20 0.64
KMT2A Q03164 4/20 0.60
MAPT P10636 3/20 0.60
MEN1 O00255 3/20 0.60
APP P05067 2/20 0.58
ESR1 P03372 2/20 0.51
CYP19A1 P11511 2/20 0.51
ESR2 Q92731 2/20 0.51
PKM P14618 1/20 0.49
ADK P55263 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA3 P07451 1/20 0.45
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9114032 0.92 ALDH1A1 (0.69) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL14664048 0.89 CASP3 (0.63) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL9065915 0.87 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL27963818 0.87 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL16451 0.87 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL13529022 0.87 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
SCHEMBL3045481 0.87 CASP3 (0.59) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL19739351 0.84 CASP3 (0.65) ALDH1A1CASP3SENP8SENP7SENP6
4-Nitroaniline SCHEMBL7158084 0.84 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL6956705 0.84 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060286311-A1 Composition for nonlinear optical material, optical element, nonlinear optical material, and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2006-12-21 US disclosed