Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.33 |
| ▸ | PKLR | P30613 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960350 | 0.76 | ESR1 (0.34) | — | |
| SCHEMBL5960228 | 0.71 | HTR2A (0.32) | PKMPKLR | |
| SCHEMBL24164160 | 0.69 | PKM (0.31) | PKMPKLR | |
| SCHEMBL15229030 | 0.69 | HSD17B10 (0.36) | — | |
| SCHEMBL29796402 | 0.67 | RECQL (0.56) | — | |
| SCHEMBL1623758 | 0.67 | IKBKE (0.43) | — | |
| SCHEMBL1113576 | 0.66 | TP53 (0.35) | PKM | |
| SCHEMBL10049570 | 0.66 | KMO (0.44) | — | |
| SCHEMBL38652613 | 0.65 | NPC1 (0.35) | — | |
| SCHEMBL2490094 | 0.62 | KMO (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682553-A1 | THIENOPYRAZOLES | Aventis Pharmaceuticals Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005026175-A1 | THIENOPYRAZOLES | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-24 | — | — | WO | disclosed |