Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960799 | 0.93 | CYP1A2 (0.44) | CYP1A2SIGMAR1 | |
| SCHEMBL960800 | 0.93 | CYP1A2 (0.44) | CYP1A2SIGMAR1 | |
| SCHEMBL8266965 | 0.93 | CYP1A2 (0.44) | CYP1A2SIGMAR1 | |
| SCHEMBL23339218 | 0.84 | — | — | |
| SCHEMBL13297841 | 0.84 | — | — | |
| SCHEMBL26619351 | 0.82 | SIGMAR1 (0.49) | CYP1A2SIGMAR1ADRA2A | |
| SCHEMBL24316031 | 0.80 | CYP1A2 (0.46) | CYP1A2SIGMAR1ADRA2A | |
| SCHEMBL9035639 | 0.80 | CYP1A2 (0.50) | CYP1A2SIGMAR1ADRA2A | |
| SCHEMBL12569118 | 0.79 | CYP1A2 (0.48) | CYP1A2SIGMAR1ADRA2A | |
| SCHEMBL26619377 | 0.79 | SIGMAR1 (0.53) | CYP1A2SIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-11040954-B1 | CXCR3 receptor agonists | RECEPTOS LLC (US) | 2021-06-22 | — | — | US | disclosed |
| US-20190345133-A1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC | 2019-11-14 | — | — | US | disclosed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20120121651-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2012-05-17 | — | — | US | disclosed |
| US-20120121651-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2012-05-17 | — | — | US | disclosed |
| US-7879849-B2 | such as 1-(2-Methylpropyl)-2-propyl-2H-pyrazolo[3,4-c]quinolin-4-amine, used as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| US-7879849-B2 | such as 1-(2-Methylpropyl)-2-propyl-2H-pyrazolo[3,4-c]quinolin-4-amine, used as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| US-7544697-B2 | Pyrazolopyridines and analogs thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544697-B2 | Pyrazolopyridines and analogs thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
| EP-0806453-B1 | Tire tread containing 3,4-polyisoprene rubber | GOODYEAR TIRE & RUBBER (US) | 2000-03-01 | — | — | EP | disclosed |
| US-5906956-A | POLYISOPRENE RUBBER POLYMERIZATION ACTIVATOR COMPRISING A LITHIUM COMPOUND, A SODIUM ALKOXIDE AND A POLAR MODIFIER, THE TIRE FORMED FROM THE RUBBER BLEND WITH IMPROVING TREAD TRACTION, WEAR AND ROLLING RESISTANCE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-05-25 | — | — | US | disclosed |
| EP-0806453-A1 | Tire tread containing 3,4-polyisoprene rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5677402-A | USING A ORGANOLITHIUM PROMOTER AND SODIUM ALKOXIDE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-14 | — | — | US | disclosed |
| US-5627237-A | PNEUMATIC TIRES WITH SULFUR CURED RUBBER COMPOSITIONS WITH NATURAL RUBBERS, POLYBUTADIENE, STYRENE-BUTADIENE RUBBER AND POLYISOPRENE FOR SKID RESISTANT TREAD | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | IKZF1, IKZF3, IKZF2 | CYP1A2 3530/4885SIGMAR1 4230/4885ADRA2A 4699/4885 |
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | IL4, IL4I1, IL2 | CYP1A2 453/4885SIGMAR1 3328/4885ADRA2A 1080/4885 |
| US-11040954-B1 | CXCR3 receptor agonists | CXCR3, CXCR1, CCR7 | CYP1A2 1702/4885SIGMAR1 368/4885ADRA2A 154/4885 |
| US-20190345133-A1 | CXCR3 RECEPTOR AGONISTS | CXCR3, CXCR1, CCR7 | CYP1A2 1702/4885SIGMAR1 368/4885ADRA2A 154/4885 |
| US-20120121651-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | IL4, IL4I1, IL2 | CYP1A2 453/4885SIGMAR1 3328/4885ADRA2A 1080/4885 |
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | IDO1, NAT1, AANAT | CYP1A2 38/4885SIGMAR1 251/4885ADRA2A 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.