Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.38 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.36 |
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.60 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL269883 | 1.00 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL21701 | 0.98 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL15846881 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL7037481 | 0.91 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL15201039 | 0.91 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL141762 | 0.91 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL446272 | 0.90 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9063855 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL27756085 | 0.89 | — | — | |
| Water SCHEMBL28252943 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399445-A1 | HIGH MOLECULAR WEIGHT POLYMERIC DISPERSIONS | SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) | 2023-12-14 | — | — | US | disclosed |
| EP-4289872-A1 | HIGH MOLECULAR WEIGHT POLYMERIC DISPERSIONS | Solenis Technologies Cayman, L.P. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-1907067-B2 | POLYMERS WITH PENDANT POLY(ALKYLENEOXY) SUBSTITUENT GROUPS AND THEIR USE IN PERSONAL CARE APPLICATIONS | SOLVAY USA INC (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016030341-A1 | METHOD FOR THE TERTIARY RECOVERY OF OIL USING HYDOPHOBICALLY ASSOCIATING COPOLYMERS WITH IMPROVED INJECTIVITY | BASF SE (DE) | 2016-03-03 | — | — | WO | disclosed |
| EP-2582733-B1 | POLYMERS COMPRISING SACCHARIDE SIDE GROUPS AND USE THEREOF | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-1907067-B1 | POLYMERS WITH PENDANT POLY(ALKYLENEOXY) SUBSTITUENT GROUPS AND THEIR USE IN PERSONAL CARE APPLICATIONS | RHODIA (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-2438097-B1 | FINE-PARTICLE, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | BASF SE (DE) | 2013-04-03 | — | — | EP | disclosed |
| CN-101222904-B | Polymers having heterocyclic substituents, monomers useful for preparing the polymers, and compositions containing the polymers | RHODIA | 2012-12-12 | — | — | CN | disclosed |
| EP-2443282-A1 | METHOD FOR REDUCING DEPOSITS IN THE DRYING SECTION IN THE MANUFACTURE OF PAPER, PAPERBOARD, AND CARDBOARD | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2438097-A1 | FINE-PARTICLE, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | BASF SE (DE) | 2012-04-11 | — | — | EP | disclosed |
| EP-0980450-A1 | METHOD FOR PRODUCING PAPER, PAPERBOARD AND CARDBOARD | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-23 | — | — | EP | disclosed |
| WO-2000004229-A1 | THE USE OF MODIFIED STARCH PRODUCTS AS RETENTION AGENTS IN THE PRODUCTION OF PAPER | STOCKHAUSEN GMBH & CO. KG (DE) | 2000-01-27 | — | — | WO | disclosed |
| EP-0952988-A1 | POLYMER-MODIFIED ANIONIC STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-03 | — | — | EP | disclosed |
| EP-0951505-A1 | POLYMER-MODIFIED STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998050630-A1 | METHOD FOR PRODUCING PAPER, PAPERBOARD AND CARDBOARD | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-12 | — | — | WO | disclosed |
| EP-0788516-B1 | CATIONIC MODIFICATION PROCESS FOR STARCH AND USE OF CATIONICALLY MODIFIED STARCH | BASF AG (DE) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998031740-A1 | POLYMER-MODIFIED STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-23 | — | — | WO | disclosed |
| WO-1998031711-A1 | POLYMER-MODIFIED ANIONIC STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-23 | — | — | WO | disclosed |
| EP-0547492-B1 | Organosol containing water-soluble polymer suspended in oil phase | STOCKHAUSEN CHEM FAB GMBH (DE) | 1998-03-11 | — | — | EP | disclosed |
| EP-0547492-A2 | Organosol containing water-soluble polymer suspended in oil phase | RÖHM GMBH (DE) | 1993-06-23 | — | — | EP | disclosed |