Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664620 | 0.94 | RXRA (0.37) | RXRARXRBRXRGNR1H4THRB | |
| SCHEMBL12733757 | 0.86 | MAPT (0.36) | RXRARXRBRXRGNR1H4THRB | |
| SCHEMBL12731125 | 0.84 | THRB (0.36) | THRBPRSS1ALDH1A1ACRMAOB | |
| SCHEMBL19759249 | 0.84 | THRB (0.39) | THRBPRSS1ACR | |
| SCHEMBL14088565 | 0.84 | THRB (0.41) | RXRARXRBRXRGNR1H4THRB | |
| SCHEMBL12154238 | 0.83 | NR1H4 (0.46) | NR1H4THRB | |
| SCHEMBL5961817 | 0.83 | KMT2A (0.39) | THRBALDH1A1 | |
| SCHEMBL5961815 | 0.83 | THRB (0.33) | THRBMAOB | |
| SCHEMBL5952860 | 0.83 | HTT (0.41) | RXRARXRBRXRGTHRBPRSS1 | |
| SCHEMBL12154225 | 0.83 | THRB (0.38) | THRBPRSS1ALDH1A1ACRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168734-B2 | Lateral alpha-substituted acrylate compound and polymer thereof | JNC CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20110144293-A1 | LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF | CHISSO CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7919648-B2 | Lateral α-substituted acrylate compound and polymer thereof | CHISSO CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144293-A1 | LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF | LEF1, AFF1, CNKSR1 | RXRA 914/4885RXRB 1359/4885RXRG 1985/4885 |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | AFF1, CNKSR1, LEF1 | RXRA 668/4885RXRB 1297/4885RXRG 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.