SCHEMBL5962865

SCHEMBL5962865

Cc1ccc(C)c(C(=O)c2ccccc2N)c1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
NPC1 O15118 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
GAA P10253 1/20 0.50
MAPK13 O15264 4/20 0.48
MAPK12 P53778 4/20 0.48
MAPK11 Q15759 4/20 0.48
MAPK14 Q16539 4/20 0.48
ESRRA P11474 1/20 0.46
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
CFTR P13569 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13955949 0.88 MAPT (0.57) MAPTNPC1MAPK1HTTMAPK13
SCHEMBL9717019 0.86 MAPK13 (0.55) MAPTNPC1MAPK1HTTGAA
SCHEMBL11753699 0.85 TSHR (0.51) HTTMAPK13MAPK12MAPK11MAPK14
SCHEMBL538169 0.83 GAA (0.59) MAPTGAAMAPK13MAPK12MAPK11
SCHEMBL9862051 0.83 MEN1 (0.57) MAPTNPC1MAPK1HTTGAA
SCHEMBL7849103 0.83 NPSR1 (0.46) MAPK1GAAALDH1A1HSD17B10KDM4E
SCHEMBL31406951 0.81 MAPT (0.49) MAPTNPC1MAPK1HTTGAA
SCHEMBL7648043 0.81 AKR1C3 (0.61) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9717031 0.79 ABCB1 (0.56) MAPTGAAMAPK13MAPK12MAPK11
SCHEMBL112507 0.79 MAPT (0.74) MAPTNPC1MAPK1GAAESRRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113557271-B Photocurable ink composition and image recording method 富士胶片株式会社 2023-06-02 CN disclosed
US-6991874-B1 Compositions suitable for electrochemical cells BASF AKTIENGESELLSCHAFT (DE) 2006-01-31 US disclosed
US-6632561-B1 Particles and dual binder composed of crosslinkable and nonreactive polymers; high temperature dimensional stability; increased lithium ion conductivity BASF AKTIENGESELLSCHAFT (DE) 2003-10-14 US disclosed
EP-1088007-B1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AG (DE) 2003-02-26 EP disclosed
US-6475663-B1 Compositions suitable for electrochemical cells BASF AKTIENGESELLSCHAFT (DE) 2002-11-05 US disclosed
EP-1138092-B1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AG (DE) 2002-09-25 EP disclosed
EP-1109841-B1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AG (DE) 2002-03-27 EP disclosed
EP-1138092-A1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2001-10-04 EP disclosed
WO-2000026977-A1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2000-05-11 WO disclosed
US-6031044-A A WATER-SOLUBLE, WATER-DISPERSIBLE POLYURETHANE COPOLYMER HAVING PHOTOINITIATOR UNITS BONDED COVALENTLY TO THE POLYMER CHAIN; CROSSLINKABLE BY IRRADIATION WITH UV LIGHT AFTER DRYING; PROTECTIVE COATINGS BASF AKTIENGESELLSCHAFT (DE) 2000-02-29 US disclosed
EP-0849300-A1 Polyurethanes with covalently bound photoinitiator-units BASF AKTIENGESELLSCHAFT (DE) 1998-06-24 EP disclosed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed