Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962865 | 0.86 | MAPT (0.51) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL11756227 | 0.85 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL13955949 | 0.84 | MAPT (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL538169 | 0.83 | GAA (0.59) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL286054 | 0.83 | LMNA (0.50) | NPC1HTTNFE2L2ALDH1A1KMT2A | |
| SCHEMBL31369141 | 0.83 | LMNA (0.50) | NPC1HTTNFE2L2ALDH1A1KMT2A | |
| SCHEMBL7837115 | 0.83 | NFE2L2 (0.46) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL22078944 | 0.81 | KMT2A (0.50) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL1787143 | 0.81 | AKR1C3 (0.66) | NFE2L2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9717038 | 0.81 | LMNA (0.54) | MAPTNPC1HTTGAANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419961-B1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10268053-B2 | UV/visible-absorbing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2019-04-23 | — | — | US | disclosed |
| EP-3419961-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | Novartis AG (CH) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017145022-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-08-31 | — | — | WO | disclosed |
| US-20170242274-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2017-08-24 | — | — | US | disclosed |
| EP-0499450-A1 | Synthesis of 1-aminoanthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5130448-A | Condensing ortho substituted benzoic acid and xylene, oxidation, ring closure, ammonolysis and decarboxyalation | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0109624-A2 | Process for producing shaped articles made from polyurethane-polyurea which may be cellular | BASF Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10268053-B2 | UV/visible-absorbing vinylic monomers and uses thereof | VCL, UACA, XRCC6 | MAPK13 3466/4885MAPK12 3065/4885MAPK11 3215/4885 |
| US-20170242274-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | VCL, UACA, XRCC6 | MAPK13 3466/4885MAPK12 3065/4885MAPK11 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.