Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001423 | 1.00 | POLB (0.36) | POLBALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL8888154 | 0.82 | THRB (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13697565 | 0.78 | POLB (0.40) | POLBALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL16280944 | 0.77 | CA2 (0.33) | — | |
| SCHEMBL7202173 | 0.77 | MGAM (0.33) | — | |
| SCHEMBL10001421 | 0.77 | MEN1 (0.39) | POLBALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL595423 | 0.77 | MEN1 (0.39) | POLBALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL21703853 | 0.76 | MMP3 (0.33) | — | |
| SCHEMBL15481368 | 0.76 | F10 (0.31) | — | |
| SCHEMBL17923804 | 0.74 | POLB (0.39) | POLBALDH1A1MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10369133-B2 | Immunosuppressive compounds and therapeutics | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2019-08-06 | — | — | US | disclosed |
| US-20160175281-A1 | IMMUNOSUPPRESSIVE COMPOUNDS AND THERAPEUTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-23 | — | — | US | disclosed |
| WO-2015013422-A1 | IMMUNOSUPPRESSIVE COMPOUNDS AND THERAPEUTICS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-01-29 | — | — | WO | disclosed |
| US-8906965-B2 | Anti-inflammatory quinic acid derivatives for radioprotection/radiomitigation | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120283331-A1 | Anti-Inflammatory Quinic Acid Derivatives for Radioprotection/Radiomitigation | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-11-08 | — | — | US | disclosed |
| US-8115031-B2 | Anti-inflammatory quinic acid derivatives for oral administration | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2012-02-14 | — | — | US | disclosed |
| EP-2219445-A1 | ANTI-INFLAMMATORY QUINIC ACID DERIVATIVES FOR ORAL ADMINISTRATION | University of Tennessee Research Foundation (US) | 2010-08-25 | — | — | EP | disclosed |
| US-20090234015-A1 | Anti-Inflammatory Quinic Acid Derivatives for Oral Administration | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-09-17 | — | — | US | disclosed |
| WO-2009062200-A1 | ANTI-INFLAMMATORY QUINIC ACID DERIVATIVES FOR ORAL ADMINISTRATION | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234015-A1 | Anti-Inflammatory Quinic Acid Derivatives for Oral Administration | NFKBIA, NFRKB, IKBKB | POLB 1426/4885ALDH1A1 2593/4885MEN1 4834/4885 |
| US-20120283331-A1 | Anti-Inflammatory Quinic Acid Derivatives for Radioprotection/Radiomitigation | NQO2, SQSTM1, CTSA | POLB 1323/4885ALDH1A1 3596/4885MEN1 4075/4885 |
| US-10369133-B2 | Immunosuppressive compounds and therapeutics | NFATC1, ICOS, TSLP | POLB 4788/4885ALDH1A1 1535/4885MEN1 3624/4885 |
| US-20160175281-A1 | IMMUNOSUPPRESSIVE COMPOUNDS AND THERAPEUTICS | NFATC1, ICOS, TSLP | POLB 4788/4885ALDH1A1 1535/4885MEN1 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.