Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963447 | 0.82 | PARP1 (0.34) | POLBALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5963823 | 0.82 | GALR1 (0.35) | POLBALDH1A1 | |
| SCHEMBL5964310 | 0.82 | ALDH1A1 (0.37) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5963571 | 0.81 | PDE7A (0.37) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5007425 | 0.80 | GALR1 (0.36) | POLBALDH1A1 | |
| SCHEMBL5963390 | 0.80 | TSHR (0.34) | POLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5963380 | 0.75 | GALR1 (0.40) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5963772 | 0.73 | AKR1B1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL5001155 | 0.72 | PTGS2 (0.37) | — | |
| SCHEMBL5963597 | 0.71 | GALR1 (0.38) | POLBALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | ACAT2 2900/4885POLB 4556/4885ALDH1A1 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.