Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963823 | 0.85 | GALR1 (0.35) | ALDH1A1POLBGALR1SLC6A3SLC6A4 | |
| SCHEMBL5963609 | 0.85 | PDE7A (0.41) | POLBGALR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5963571 | 0.85 | PDE7A (0.37) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5007425 | 0.84 | GALR1 (0.36) | ALDH1A1POLBGALR1PTGS2MAPT | |
| SCHEMBL5007455 | 0.82 | PTGS2 (0.43) | PTGS2KMT2ASMN1; SMN2 | |
| SCHEMBL5004773 | 0.77 | ALDH1A1 (0.36) | ALDH1A1POLBPLA2G7MEN1KMT2A | |
| SCHEMBL5963380 | 0.75 | GALR1 (0.40) | ALDH1A1POLBGALR1MAPTMEN1 | |
| SCHEMBL5963597 | 0.71 | GALR1 (0.38) | ALDH1A1POLBGALR1SMN1; SMN2 | |
| SCHEMBL5964141 | 0.71 | GRIA2 (0.36) | ALDH1A1GALR1 | |
| SCHEMBL5963305 | 0.65 | SLC6A3 (0.39) | ALDH1A1SLC6A3SLC6A4SLC6A2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | ALDH1A1 4282/4885POLB 4556/4885GALR1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.