Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964017 | 0.85 | GRIN1 (0.36) | DRD2HTTSLC6A2ALDH1A1SLC6A4 | |
| SCHEMBL5963651 | 0.84 | GALR1 (0.39) | HSD11B1GALR1SLC6A2ALDH1A1SLC6A4 | |
| SCHEMBL5963922 | 0.82 | GALR1 (0.38) | HSD11B1GALR1MEN1KMT2ASLC6A2 | |
| SCHEMBL5964149 | 0.78 | GALR1 (0.37) | HSD11B1GALR1L3MBTL1ALDH1A1 | |
| SCHEMBL5964213 | 0.77 | HSD11B1 (0.33) | HSD11B1DRD2DRD4L3MBTL1SLC6A2 | |
| SCHEMBL6820982 | 0.77 | KDM4E (0.36) | ADORA2BHSD11B1DRD2DRD4KDM4E | |
| SCHEMBL5963530 | 0.76 | PGR (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5964239 | 0.74 | ELANE (0.34) | HSD11B1KDM4EMEN1HTTKMT2A | |
| SCHEMBL5963823 | 0.70 | GALR1 (0.35) | GALR1KDM4ESLC6A2ALDH1A1SLC6A4 | |
| SCHEMBL5963859 | 0.68 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | ADORA2B 3395/4885HSD11B1 1622/4885GALR1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.