Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964017 | 0.84 | GRIN1 (0.36) | NPC1RAB9AALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL5964149 | 0.76 | GALR1 (0.37) | GALR1PGRHSD11B1NPC1RAB9A | |
| SCHEMBL5963859 | 0.67 | SLC6A2 (0.33) | SLC6A2SLC6A3SLC6A4THRB | |
| SCHEMBL3487270 | 0.66 | CA12 (0.48) | PGRALDH1A1TP53BACE1 | |
| SCHEMBL5963530 | 0.65 | PGR (0.42) | PGRNPC1RAB9AALDH1A1 | |
| SCHEMBL5963561 | 0.64 | SLC6A2 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3487936 | 0.63 | CA12 (0.45) | PGRALDH1A1TP53 | |
| SCHEMBL817554 | 0.58 | ALOX5 (0.65) | PGRNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL31222672 | 0.58 | ALOX5 (0.65) | PGRNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL20340419 | 0.57 | OPRM1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | GALR1 404/4885PGR 813/4885HSD11B1 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.