Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963585 | 0.88 | POLB (0.42) | AKR1B1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL5963527 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1HTTSSTR3 | |
| SCHEMBL5964489 | 0.86 | FPR2 (0.40) | AKR1B1KMT2A | |
| SCHEMBL5963733 | 0.86 | PDE7A (0.41) | PDE7AKMT2ATDP1PTGS2 | |
| SCHEMBL5963658 | 0.86 | AKR1B1 (0.40) | AKR1B1PDE7AKMT2AGSK3BALDH1A1 | |
| SCHEMBL5963932 | 0.85 | KMT2A (0.40) | PDE7AKMT2AALDH1A1TDP1 | |
| SCHEMBL5964441 | 0.83 | PDE7A (0.42) | AKR1B1NPC1PDE7AMEN1KMT2A | |
| SCHEMBL5963581 | 0.83 | PDE7A (0.42) | AKR1B1NPC1PDE7AMEN1KMT2A | |
| SCHEMBL5963591 | 0.81 | SLC6A4 (0.43) | AKR1B1PDE7AKMT2ATDP1 | |
| SCHEMBL5963594 | 0.77 | PDE7A (0.46) | AKR1B1NPC1PDE7AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | AKR1B1 4086/4885NPC1 4150/4885PDE7A 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.