Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | ACACA | Q13085 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963585 | 0.90 | POLB (0.42) | AKR1B1PDE7BKMT2AALDH1A1LMNA | |
| SCHEMBL5964489 | 0.88 | FPR2 (0.40) | AKR1B1FPR2PDE7BKMT2ALMNA | |
| SCHEMBL5963527 | 0.88 | ALDH1A1 (0.42) | PDE7BKMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL5963733 | 0.88 | PDE7A (0.41) | PDE7BPDE7AKMT2ALMNA | |
| SCHEMBL5963932 | 0.88 | KMT2A (0.40) | PDE7BPDE7AKMT2AALDH1A1LMNA | |
| SCHEMBL5963591 | 0.87 | SLC6A4 (0.43) | AKR1B1PDE7BPDE7AKMT2A | |
| SCHEMBL5963769 | 0.86 | PDE7B (0.39) | AKR1B1PDE7BPDE7AGSK3B | |
| SCHEMBL5963923 | 0.86 | AKR1B1 (0.43) | AKR1B1PDE7AKMT2AGSK3BALDH1A1 | |
| SCHEMBL5963968 | 0.81 | PDE7B (0.38) | PDE7BPDE7AKMT2AGSK3BLMNA | |
| SCHEMBL5963955 | 0.81 | RECQL (0.39) | FPR2KMT2AGSK3BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | AKR1B1 4086/4885FPR2 2452/4885PDE7B 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.