Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.45 |
| ▸ | CDC25B | P30305 | 5/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239415 | 0.79 | MAOB (0.58) | PTPN1PARP15PARP10MAOBPARP14 | |
| SCHEMBL8877502 | 0.79 | PARP10 (0.58) | PTPN1PARP15PARP10MAOBPARP14 | |
| SCHEMBL2216320 | 0.79 | ALOX5 (0.67) | MAOBNPC1RAB9A | |
| SCHEMBL863430 | 0.78 | MAOB (0.60) | PARP15PARP10MAOBPARP14NPC1 | |
| SCHEMBL12443168 | 0.78 | PTPN1 (0.53) | PTPN1PARP15PARP10MAOBPARP14 | |
| SCHEMBL920290 | 0.77 | MAOB (0.51) | PARP15PARP10MAOBPARP14NPC1 | |
| SCHEMBL7617555 | 0.77 | MAOB (0.49) | MAOB | |
| SCHEMBL8876594 | 0.75 | PTPN1 (0.60) | PTPN1PARP15PARP10MAOBPARP14 | |
| SCHEMBL8877320 | 0.75 | PTPN1 (0.64) | PTPN1PARP15PARP10MAOBPARP14 | |
| SCHEMBL5397207 | 0.75 | PTPN1 (0.60) | PTPN1PARP15PARP10MAOBPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131310-B1 | CHRYSTALS OF 5- 6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEM CORP (JP) | 2006-01-11 | — | — | EP | disclosed |
| EP-1131310-A1 | CHRYSTALS OF 5- 6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-12 | — | — | EP | disclosed |