Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 3/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254366 | 0.92 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1MAPTTXNRD1MAPK1 | |
| SCHEMBL381701 | 0.80 | MERTK (0.51) | L3MBTL1MAPTHTTMERTKGSR | |
| SCHEMBL29392605 | 0.80 | MERTK (0.51) | L3MBTL1MAPTHTTMERTKGSR | |
| SCHEMBL3246716 | 0.70 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTTXNRD1GSTP1 | |
| SCHEMBL30271385 | 0.69 | MAPT (0.53) | L3MBTL1MAPTHTTMERTKGSR | |
| SCHEMBL8710611 | 0.69 | MAPT (0.53) | L3MBTL1MAPTHTTMERTKGSR | |
| SCHEMBL21623745 | 0.68 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1MAPTHTTTXNRD1 | |
| SCHEMBL952538 | 0.67 | CTSB (0.47) | ALDH1A1L3MBTL1MAPTTDP1CTSB | |
| SCHEMBL14658918 | 0.67 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTTXNRD1TDP1 | |
| SCHEMBL21436535 | 0.67 | MAPT (0.49) | ALDH1A1L3MBTL1MAPTHTTMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685090-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005042464-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2005-05-12 | — | — | WO | disclosed |