Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29211109 | 0.82 | RIPK1 (0.48) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL94698 | 0.80 | LMNA (0.54) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL9066616 | 0.79 | ALDH1A1 (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL3081755 | 0.76 | RIPK1 (0.64) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL5185803 | 0.76 | RIPK1 (0.64) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL27692795 | 0.76 | RIPK1 (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL2496078 | 0.76 | RIPK1 (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL2939704 | 0.76 | RIPK1 (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL29860819 | 0.74 | RIPK1 (0.61) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL8710104 | 0.74 | RIPK1 (0.61) | RIPK1LMNAKDM4EL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115019-B2 | Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-02-14 | — | — | US | disclosed |
| US-8115019-B2 | Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-02-14 | — | — | US | disclosed |
| WO-2009104849-A1 | CIS-2,6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104849-A1 | CIS-2,6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-08-27 | — | — | WO | disclosed |
| US-20090209770-A1 | CIS-2, 6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-08-20 | — | — | US | disclosed |
| US-20090209770-A1 | CIS-2, 6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209770-A1 | CIS-2, 6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF | TYMS, DHFR, FDPS | RIPK1 4222/4885LMNA 3109/4885KDM4E 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.