SCHEMBL598380

SCHEMBL598380

CC(O)Oc1ccccc1.NC(=O)NN1CCNC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
OPRD1 P41143 2/20 0.36
KMT2A Q03164 1/20 0.35
PRMT5 O14744 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRM1 P11229 1/20 0.34
TSHR P16473 1/20 0.34
LTB4R Q15722 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Salicylate SCHEMBL28135754 0.80 TSHR (0.34) KMT2ATSHR
Benzoic Acid SCHEMBL15657396 0.74 CA2 (0.46) POLBOPRD1TSHR
SCHEMBL28189279 0.73 GNAI3 (0.34)
SCHEMBL27888790 0.73 GNAI3 (0.34)
SCHEMBL7527875 0.73 GNAI3 (0.34)
Urea SCHEMBL6942842 0.73 GNAI3 (0.34)
Ammonia Solution, Strong SCHEMBL28242181 0.73 GNAI3 (0.34)
Nitrogen SCHEMBL20898038 0.72 GNAI3 (0.33)
Paraben SCHEMBL2591112 0.70 CA2 (0.44) POLBOPRD1KMT2ATSHR
Glycerin SCHEMBL9450682 0.70 GNAI3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033248-A1 COMPOSITIONS AND METHODS FOR ENHANCED DECONTAMINATION PARVINI AMIR REZA SALAR (US) 2023-02-02 US disclosed
EP-3897704-A1 TOPICAL FORMULATIONS FOR THE DELIVERY OF MICROBIALLY DERIVED MATERIALS Matrisys Bioscience, Inc. (US) 2021-10-27 EP disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
US-10980510-B2 Ultrasound probe couplers and related methods Scully, Casey K. (US) 2021-04-20 US disclosed
WO-2020131997-A1 TOPICAL FORMULATIONS FOR THE DELIVERY OF MICROBIALLY DERIVED MATERIALS MATRISYS BIOSCIENCE, INC. (US) 2020-06-25 WO disclosed
US-20200093785-A1 SKIN CARE COMPOSITIONS AND METHODS STAUFF DEIDRA (US) 2020-03-26 US disclosed
US-20190336434-A1 Antiperspirant Formulation Containing Non-Aluminum Metal And Essential Oil GULBRANDSEN TECHNOLOGIES, INC. (US) 2019-11-07 US disclosed
EP-3563824-A1 ANTIPERSPIRANT FORMULATION CONTAINING NON-ALUMINUM METAL AND ESSENTIAL OIL Gulbrandsen Technologies, Inc. (US) 2019-11-06 EP disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US disclosed
US-20080175875-A1 COSMETIC COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY 2008-07-24 US disclosed
WO-2008039466-A1 COSMETIC COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-03 WO disclosed
WO-2007136586-A2 PERSONAL CARE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-29 WO disclosed
US-20070269392-A1 Personal care compositions Covation Inc. 2007-11-22 US disclosed
EP-1501468-A1 RINSABLE SKIN CONDITIONING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2005-02-02 EP disclosed
US-6699488-B2 OIL IN WATER EMULSION HAVING HIGH DEPOSITION EFFICIENCY, SURFACTANT FREE THE PROCTER & GAMBLE COMPANY 2004-03-02 US disclosed
WO-2003094866-A1 RINSABLE SKIN CONDITIONING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-11-20 WO disclosed
WO-2003094867-A1 RINSABLE SKIN CONDITIONING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-11-20 WO disclosed
US-20030211069-A1 Rinsable skin conditioning compositions THE PROCTER & GAMBLE COMPANY 2003-11-13 US disclosed
US-20030211061-A1 Rinsable skin conditioning compositions THE PROCTER & GAMBLE COMPANY 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 POLB 4609/4885OPRD1 223/4885KMT2A 3630/4885
US-20080175875-A1 COSMETIC COMPOSITIONS POLE3, POLD3, PARG POLB 266/4885OPRD1 2902/4885KMT2A 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.