Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL18938860 | 0.77 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL26085056 | 0.76 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL1065204 | 0.76 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL36683 | 0.76 | — | — | |
| SCHEMBL8766333 | 0.75 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28790272 | 0.74 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL155436 | 0.74 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL632264 | 0.73 | ZDHHC20 (0.75) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL1561467 | 0.73 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL476500 | 0.73 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128663-A1 | Aryl boronate functionalized polymers for treating obesity | GENZYME CORPORATION (US) | 2006-06-15 | — | — | US | disclosed |
| US-7041280-B2 | Aryl boronate functionalized polymers for treating obesity | GENZYME CORPORATION (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1404686-A1 | ARYL BORONATE FUNCTIONALIZED POLYMERS FOR TREATING OBESITY | Geltex Pharmaceuticals, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20030059399-A1 | Aryl boronate functionalized polymers for treating obesity | GELTEX PHARMACEUTICALS, INC. | 2003-03-27 | — | — | US | disclosed |
| WO-2003002571-A1 | ARYL BORONATE FUNCTIONALIZED POLYMERS FOR TREATING OBESITY | GENZYME CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030059399-A1 | Aryl boronate functionalized polymers for treating obesity | CEL, AHR, LIPE | ZDHHC20 598/4885ZDHHC2 573/4885TSHR 288/4885 |
| US-20060128663-A1 | Aryl boronate functionalized polymers for treating obesity | CEL, AHR, LIPE | ZDHHC20 560/4885ZDHHC2 503/4885TSHR 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.