Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 14/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 14/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593400 | 0.82 | NR1H2 (0.54) | NR1H2NR1H3CNR2SLC2A1KDM4E | |
| SCHEMBL8958343 | 0.80 | NR1H2 (0.51) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL107013 | 0.80 | CNR2 (0.49) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL17663673 | 0.78 | CNR2 (0.49) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL14564613 | 0.78 | CNR2 (0.49) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL17431102 | 0.78 | CNR2 (0.49) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL18074044 | 0.78 | CNR2 (0.48) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2141325 | 0.78 | CNR2 (0.48) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL7153351 | 0.78 | EGFR (0.50) | NR1H2NR1H3CNR2KDM4EALDH1A1 | |
| SCHEMBL8084635 | 0.78 | NR1H2 (0.43) | NR1H2NR1H3ALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250262308-A1 | Compositions and Methods for Modulating Dopamine Receptor Activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-08-21 | — | — | US | disclosed |
| CN-111315762-B | Optically controlled switch with affinity tag and method of use thereof | 加利福尼亚大学董事会 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023220526-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230173090-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-08 | — | — | US | disclosed |
| WO-2023097186-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-4172187-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | The Regents of the University of California (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-4158002-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | The Regents of the University of California (US) | 2023-04-05 | — | — | EP | disclosed |
| WO-2022006071-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2021243086-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-02 | — | — | WO | disclosed |
| US-20210369744-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| US-8309350-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120190094-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-26 | — | — | US | disclosed |
| US-8178496-B2 | Photoreactive regulator of glutamate receptor function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-15 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110207213-A1 | Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof | ENERGY, UNITED STATES DEPARTMENT OF | 2011-08-25 | — | — | US | disclosed |
| US-20100330607-A1 | PHOTOSWITCH-ENABLED ION CHANNEL ASSAY SYSTEM | PHOTOSWITCH BIOSCIENCES, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | ENERGY, UNITED STATE DEPARTMENT OF | 2009-07-16 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
| US-6087072-A | Article having a light-controllable super-water-repellent surface and a printing machine using the article | HITACHI, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |
| US-6027852-A | Article having a light-controllable super-water-repellent surface and a printing machine using the article | HITACHI, LTD. (JP) | 2000-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369744-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | PDE6C, UACA, EPHA2 | NR1H2 2348/4885NR1H3 1866/4885CNR2 2754/4885 |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | GRM2, GRM1, GRM3 | NR1H2 1513/4885NR1H3 1698/4885CNR2 240/4885 |
| US-20230173090-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | PARK7, PRLHR, SNCA | NR1H2 2123/4885NR1H3 2030/4885CNR2 637/4885 |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | PPP1R10, PPP6R3, ANKRD52 | NR1H2 3711/4885NR1H3 3990/4885CNR2 3445/4885 |
| US-20110207213-A1 | Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof | PPP1R10, PPP6R1, PPP6R3 | NR1H2 4217/4885NR1H3 4359/4885CNR2 4322/4885 |
| US-20250262308-A1 | Compositions and Methods for Modulating Dopamine Receptor Activity | PARK7, PRLHR, SNCA | NR1H2 2891/4885NR1H3 2826/4885CNR2 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.