SCHEMBL5994409

SCHEMBL5994409

CCC1C(C(=O)O)=C(C)N(CC)C(C)=C1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
PYGM P11217 6/20 0.38
PYGL P06737 5/20 0.38
LMNA P02545 3/20 0.37
RECQL P46063 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
APOBEC3A P31941 2/20 0.35
APOBEC3G Q9HC16 2/20 0.35
HTT P42858 1/20 0.33
PABPC1 P11940 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8037227 0.72 SMN1; SMN2 (0.49) ALDH1A1SMN1; SMN2PYGMPYGLLMNA
SCHEMBL9797407 0.70 GAA (0.46) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL2699668 0.62 PYGM (0.33) PYGMPYGLLMNA
SCHEMBL2853254 0.59 F2 (0.57) ALDH1A1LMNA
SCHEMBL10336238 0.58 F2 (0.42) ALDH1A1LMNARECQLMEN1KMT2A
SCHEMBL2701387 0.57 L3MBTL1 (0.34)
SCHEMBL9812716 0.55 FFAR3 (0.36)
SCHEMBL15825651 0.53 F2 (0.48) ALDH1A1LMNAHTT
SCHEMBL19103223 0.53 F2 (0.35) ALDH1A1LMNA
SCHEMBL14275464 0.53 F2 (0.48) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113248457-B Substrate for synthesizing beta-Se amino acid, and preparation method and application thereof 上海交通大学 2024-05-17 CN claimed
CN-117623925-A Method for deoxidizing and converting photocatalytic alcohol 同济大学 2024-03-01 CN claimed
CN-117304081-A Method for synthesizing homoallylic alcohol compound by synergistic catalysis of visible light and titanium 河南师范大学 2023-12-29 CN claimed
CN-117105764-A Method for preparing cis-15-tetracosenoic acid from erucic acid peroxide 山东省农业科学院 2023-11-24 CN claimed
CN-115417759-B Method for preparing nervonic acid by using erucic acid redox active ester 山东省农业科学院 2023-11-07 CN claimed
CN-115974891-B Preparation method of norcantharidin 仁和堂药业有限公司 2023-07-25 CN claimed
CN-115007177-B CdSeS phantom number nanocluster and application thereof as photocatalyst 四川大学 2023-06-23 CN claimed
CN-115888841-B Organic amine coordinated CdSe nano sheet and application thereof as photocatalyst 四川大学 2023-05-30 CN claimed
CN-114315894-B Chiral alpha-aryl phosphate, chiral alpha-aryl phosphine compound and synthesis thereof 同济大学 2023-05-26 CN claimed
CN-116023377-A Preparation method of non-nereirenone and key chiral intermediate thereof 杭州科巢生物科技有限公司 2023-04-28 CN claimed
CN-116023401-A Preparation method of chiral borate compound 同济大学 2023-04-28 CN claimed
WO-2025056065-A1 CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE 上海医药集团股份有限公司 2025-03-20 WO disclosed
CN-114292304-B Method for synthesizing aryl alkyne lead compound 康龙化成(宁波)科技发展有限公司 2024-07-09 CN disclosed
CN-118234734-A Pyrimidine tricyclic derivatives and their use in medicine 正大天晴药业集团股份有限公司 2024-06-21 CN disclosed
CN-113248457-B Substrate for synthesizing beta-Se amino acid, and preparation method and application thereof 上海交通大学 2024-05-17 CN disclosed
US-6630509-B2 Pharmaceutical medication associated with insulin resistance; patient with prophylaxis conditions having reduced sensitivity to insulin ASTRAZENECA AB (SE) 2003-10-07 US disclosed
US-6630600-B1 Intermediate for their manufacture, pharmaceutical preparations containing them and the use of the compounds in clinical conditions associated with insulin resistance. ASTRAZENECA AB (SE) 2003-10-07 US disclosed
EP-1084102-B1 NEW 3-ARYL PROPIONIC ACID DERIVATIVES AND ANALOGS ASTRAZENECA AB (SE) 2003-10-01 EP disclosed
US-20030018207-A1 Phenalkyloxy-phenyl derivatives ASTRAZENECA AB (SE) 2003-01-23 US disclosed
US-6288096-B1 ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS ASTRAZENECA AB (SE) 2001-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018207-A1 Phenalkyloxy-phenyl derivatives GPR119, INSR, IAPP ALDH1A1 1255/4885SMN1; SMN2 2155/4885PYGM 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.