SCHEMBL5994516

SCHEMBL5994516

CCCCPC(=O)c1c(CC)cccc1CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
BID P55957 6/20 0.41
MCL1 Q07820 6/20 0.41
BCL2L1 Q07817 5/20 0.41
BAK1 Q16611 5/20 0.41
KAT8 Q9H7Z6 3/20 0.41
PPARA Q07869 3/20 0.41
PPARG P37231 2/20 0.41
EP300 Q09472 2/20 0.41
KAT5 Q92993 2/20 0.41
SAE1 Q9UBE0 2/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5997453 0.82 ALDH1A1 (0.44) MAPTMEN1ALDH1A1HTTKMT2A
SCHEMBL5998257 0.82 F2R (0.38) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5996822 0.82 PTGER1 (0.43) KDM4E
SCHEMBL5997773 0.81 GABRA1 (0.46) GABRA1GABRB2BIDMCL1BCL2L1
SCHEMBL5994691 0.81 MEN1 (0.37) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5997294 0.77 L3MBTL1 (0.42) PPARAMAPTMEN1KMT2AKDM4E
SCHEMBL5996916 0.76 TYK2 (0.40) ALDH1A1HTTPOLB
SCHEMBL5996501 0.75 GABRA1 (0.41) GABRA1GABRB2BIDMCL1BCL2L1
SCHEMBL5994553 0.74 PLA2G2A (0.34) MAPTMEN1ALDH1A1HTTKMT2A
SCHEMBL5997733 0.74 TSHR (0.38) ALDH1A1HTTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109250-B2 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2006-09-19 US disclosed
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-20050004247-A1 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. 2005-01-06 US disclosed
EP-1446410-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES Ciba SC Holding AG (CH) 2004-08-18 EP disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
WO-2003044030-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 GABRA1 2372/4885GABRB2 2252/4885BID 2767/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 GABRA1 3077/4885GABRB2 2736/4885BID 4654/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 GABRA1 3354/4885GABRB2 3498/4885BID 2885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.