SCHEMBL5994679

SCHEMBL5994679

Cc1cccc(C)c1C(=O)P(=O)(CC(C)CC(C)(C)C)C(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRN P28799 2/20 0.33
SORT1 Q99523 2/20 0.33
UTS2R Q9UKP6 1/20 0.32
S1PR2 O95136 1/20 0.31
S1PR4 O95977 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
S1PR3 Q99500 1/20 0.31
S1PR5 Q9H228 1/20 0.31
TYK2 P29597 1/20 0.31
F2R P25116 1/20 0.30
CCKBR P32239 1/20 0.30
CNR2 P34972 1/20 0.30
MRGPRX4 Q96LA9 1/20 0.30
HPGD P15428 1/20 0.30
ABL1 P00519 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995059 0.92 TYK2 (0.38) UTS2RTYK2ABL1SRC
SCHEMBL5995206 0.89 L3MBTL1 (0.34) GRNSORT1HTT
SCHEMBL125225 0.89 L3MBTL1 (0.34) F2R
SCHEMBL5997253 0.88 GRN (0.33) GRNSORT1
SCHEMBL5993788 0.86 MEN1 (0.36) LMNAHTTTYK2
SCHEMBL5996661 0.85 LMNA (0.34) LMNANPSR1F2RHPGD
SCHEMBL5994701 0.85 GRM5 (0.34) HPGD
SCHEMBL5994354 0.85 UTS2R (0.36) UTS2RS1PR2S1PR4LMNAHTT
SCHEMBL610990 0.85 ALDH1A1 (0.36) LMNANPSR1TYK2F2RHPGD
SCHEMBL5995856 0.85 RAB9A (0.36) NPSR1TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 GRN 4022/4885SORT1 4371/4885UTS2R 2725/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 GRN 2902/4885SORT1 1404/4885UTS2R 2574/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 GRN 2020/4885SORT1 3562/4885UTS2R 2430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.