SCHEMBL5995206

SCHEMBL5995206

Cc1cc(C)c(C(=O)P(=O)(CC(C)CC(C)(C)C)C(=O)c2c(Cl)cc(Cl)cc2Cl)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.34
GRN P28799 1/20 0.34
SORT1 Q99523 1/20 0.34
HTT P42858 1/20 0.32
KDM4E B2RXH2 1/20 0.31
KCNH2 Q12809 1/20 0.30
CACNA1I Q9P0X4 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5997253 0.92 GRN (0.33) GRNSORT1
SCHEMBL611535 0.90 L3MBTL1 (0.36) L3MBTL1KDM4EMEN1KMT2A
SCHEMBL5993788 0.89 MEN1 (0.36) L3MBTL1HTTMEN1KMT2A
SCHEMBL5994679 0.89 GRN (0.33) GRNSORT1HTT
SCHEMBL5995314 0.85 KDM4E (0.33) L3MBTL1KDM4EMEN1KMT2A
SCHEMBL5995524 0.85 KMT2A (0.33) L3MBTL1GRNSORT1KDM4EMEN1
SCHEMBL5996661 0.84 LMNA (0.34) L3MBTL1KDM4EMEN1KMT2A
SCHEMBL14641678 0.83 KDM4E (0.37) L3MBTL1KDM4EMEN1KMT2A
SCHEMBL5995856 0.81 RAB9A (0.36) L3MBTL1
SCHEMBL5995257 0.81 TAS1R3 (0.34) L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 L3MBTL1 1852/4885GRN 4022/4885SORT1 4371/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 L3MBTL1 1879/4885GRN 2902/4885SORT1 1404/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 L3MBTL1 2570/4885GRN 2020/4885SORT1 3562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.