Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437090 | 0.85 | POLB (0.42) | POLBNPC1RAB9AHPGDIKBKB | |
| SCHEMBL19065135 | 0.81 | BCAT2 (0.44) | RAB9AHPGDIKBKBALDH1A1MAPT | |
| SCHEMBL10587901 | 0.71 | KIF11 (0.38) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5487334 | 0.71 | CYP1A2 (0.42) | POLBNPC1HPGDIKBKBALDH1A1 | |
| SCHEMBL5479979 | 0.71 | ALDH1A1 (0.41) | NPC1RAB9AIKBKBALDH1A1MAPT | |
| SCHEMBL10766968 | 0.69 | ALDH1A1 (0.50) | POLBNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL6611507 | 0.69 | ALDH1A1 (0.34) | POLBALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL11673948 | 0.69 | SMN1; SMN2 (0.36) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL81434 | 0.68 | POLB (0.75) | POLBNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL100932 | 0.68 | TSHR (0.39) | NPC1RAB9AHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917462-B1 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060030553-A1 | Cell adhesion inhibitors | ZHENG ZHONGLI | 2006-02-09 | — | — | US | disclosed |
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040053907-A1 | Cell adhesion inhibitors | BIOGEN, INC. A MASSACHUSETTS CORPORATION. | 2004-03-18 | — | — | US | disclosed |
| US-6686350-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2004-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053907-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | POLB 4750/4885NPC1 2649/4885RAB9A 1779/4885 |
| US-20060030553-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | POLB 4750/4885NPC1 2649/4885RAB9A 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.