Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997088 | 0.87 | RORC (0.42) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13954541 | 0.83 | RORC (0.46) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5996866 | 0.81 | RORC (0.37) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4704464 | 0.80 | RAB9A (0.62) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4704685 | 0.79 | MAPT (0.61) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13154827 | 0.79 | MAPT (0.46) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22690991 | 0.79 | MAPT (0.61) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29423180 | 0.79 | MAPT (0.61) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5997266 | 0.78 | MAPT (0.66) | RORCKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5995320 | 0.77 | RORC (0.37) | RORCALDH1A1SMN1; SMN2NPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | SCHERING CORPORATION | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | KIFC1, KIF5B, KIF2C | RORC 2343/4885KDM4E 501/4885ALDH1A1 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.