Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997371 | 0.72 | SIGMAR1 (0.48) | HSD11B1SIGMAR1MEN1KMT2ALMNA | |
| SCHEMBL7619856 | 0.72 | SIGMAR1 (0.53) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27564929 | 0.64 | GRIN2D (0.61) | SIGMAR1RAB9AGRIN2DGRIN3BGRIN1 | |
| Sulfuric Acid SCHEMBL28378280 | 0.63 | LMNA (0.55) | SIGMAR1MEN1KMT2ALMNARAB9A | |
| SCHEMBL4628458 | 0.63 | USP2 (0.48) | LMNASMN1; SMN2USP2 | |
| Iodobenzene SCHEMBL28516977 | 0.62 | P2RX7 (0.50) | HSD11B1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3455674 | 0.61 | HSD11B1 (0.49) | HSD11B1MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL2849063 | 0.60 | MEN1 (0.50) | HSD11B1MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL3455152 | 0.58 | HSD11B1 (0.71) | HSD11B1MEN1KMT2ARAB9ACYP3A4 | |
| SCHEMBL14859407 | 0.58 | HSD11B1 (0.43) | HSD11B1MEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041702-B1 | Pharmaceutically active compounds and methods of use | SCION PHARMACEUTICALS, INC. (US) | 2006-05-09 | — | — | US | claimed |