Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995320 | 0.89 | RORC (0.37) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL5997295 | 0.82 | RORC (0.35) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL4704470 | 0.81 | RORC (0.37) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL4702022 | 0.79 | MAPT (0.40) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL13954944 | 0.78 | TP53 (0.34) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL13954593 | 0.78 | TP53 (0.34) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL4702415 | 0.77 | MAPT (0.40) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL22691739 | 0.77 | MAPT (0.40) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL22699253 | 0.77 | ALDH1A1 (0.39) | RORCTP53POLBMAPTALDH1A1 | |
| SCHEMBL29926097 | 0.77 | MAPT (0.40) | RORCTP53POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | SCHERING CORPORATION | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | KIFC1, KIF5B, KIF2C | RORC 2343/4885CA2 4033/4885TP53 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.