Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998393 | 1.00 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL2179945 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1TSHR | |
| SCHEMBL29039008 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1TSHR | |
| SCHEMBL28648606 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1TSHR | |
| SCHEMBL3041677 | 0.76 | ABCC4 (0.46) | MAPTABCC4ALDH1A1LMNATSHR | |
| Acetic Acid SCHEMBL27565407 | 0.74 | MAPT (0.61) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL4904722 | 0.74 | MAPT (0.45) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL1697837 | 0.74 | ACLY (0.41) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL2894770 | 0.74 | ACLY (0.61) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3968169 | 0.74 | ABCC4 (0.45) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038043-B1 | Glycosylated indolocarbazole synthesis | YALE UNIVERSITY (US) | 2006-05-02 | — | — | US | disclosed |
| WO-1997007081-A2 | GLYCOSYLATED INDOLOCARBAZOLE SYNTHESIS | YALE UNIVERSITY (US) | 1997-02-27 | — | — | WO | disclosed |