Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP7 | P09237 | 3/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599789 | 0.85 | ALDH1A1 (0.41) | ADAMTS5TDP1MMP1MMP7MMP12 | |
| SCHEMBL14676567 | 0.84 | ADAMTS5 (0.56) | ADAMTS5TDP1ADAMTS4ESR1NR1I2 | |
| SCHEMBL12830369 | 0.84 | TDP1 (0.49) | TDP1MMP1MMP7MMP12MMP13 | |
| SCHEMBL27642228 | 0.84 | ADAMTS5 (0.52) | ADAMTS5MMP12MMP13ADAMTS4HSD11B1 | |
| SCHEMBL28758085 | 0.84 | ADAMTS5 (0.52) | ADAMTS5MMP12MMP13ADAMTS4HSD11B1 | |
| SCHEMBL28171647 | 0.81 | ADAMTS5 (0.50) | ADAMTS5ADAMTS4HSD11B1KEAP1NFE2L2 | |
| SCHEMBL27725761 | 0.80 | ADAMTS5 (0.54) | ADAMTS5ADAMTS4L3MBTL1ESR1HSD11B1 | |
| SCHEMBL599788 | 0.80 | CNR2 (0.49) | ADAMTS5MMP1MMP7MMP12MMP13 | |
| SCHEMBL21820681 | 0.80 | TDP1 (0.44) | TDP1MMP1MMP7MMP12MMP13 | |
| SCHEMBL23357778 | 0.78 | ALDH1A1 (0.44) | TDP1ESR1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9068137-B2 | Water-mixed metal working fluids containing ether pyrrolidone carboxylic acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-06-30 | — | — | US | disclosed |
| US-8759264-B2 | Water-based hydraulic fluids comprising dithio-di(aryl carbolic acids) | CLARIENT FINANCE (BVI) LIMITED (VG) | 2014-06-24 | — | — | US | disclosed |
| US-20120088706-A1 | WATER-MIXED METAL WORKING FLUIDS CONTAINING ETHER PYRROLIDONE CARBOXYLIC ACIDS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | disclosed |
| US-20120088705-A1 | POLYALKYLENE GLYCOL-BASED ETHER PYRROLIDONE CARBOXYLIC ACIDS, AND CONCENTRATES FOR THE PRODUCTION OF SYNTHETIC COOLING LUBRICANTS CONTAINING THE SAME | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | disclosed |
| US-20120040875-A1 | Water-Based Hydraulic Fluids Comprising Dithio-Di(Aryl Carbolic Acids) | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-02-16 | — | — | US | disclosed |
| US-4911888-A | Salt containing phenyl ring | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4344862-A | Reaction products of sulfonamido-carboxylic acids or carboxamido-carboxylic acids with alkanolamines, and their use as low-foaming corrosion inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088705-A1 | POLYALKYLENE GLYCOL-BASED ETHER PYRROLIDONE CARBOXYLIC ACIDS, AND CONCENTRATES FOR THE PRODUCTION OF SYNTHETIC COOLING LUBRICANTS CONTAINING THE SAME | F12, ADH1A, ADH1C | ADAMTS5 4100/4885TDP1 1000/4885MMP1 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.