Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600070 | 0.85 | ADAMTS5 (0.51) | ADAMTS5MAPK1PTGESALOX5MMP1 | |
| SCHEMBL599788 | 0.77 | CNR2 (0.49) | ADAMTS5PTGESALOX5PPARGMMP1 | |
| SCHEMBL3693999 | 0.76 | TSHR (0.49) | ALDH1A1HCRTR2JAK2KMT2AMEN1 | |
| SCHEMBL2583710 | 0.74 | TSHR (0.57) | ALDH1A1HCRTR2JAK2KMT2AMEN1 | |
| SCHEMBL9307793 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HCRTR2KMT2AMEN1MAPK1 | |
| SCHEMBL5505271 | 0.74 | CA12 (0.48) | ALDH1A1HCRTR2JAK2KMT2AMEN1 | |
| SCHEMBL600044 | 0.73 | ITGAV (0.62) | ALDH1A1SLC1A3SLC1A2SLC1A1ITGAV | |
| SCHEMBL5507153 | 0.73 | CA12 (0.47) | ALDH1A1HCRTR2KMT2AMEN1MAPT | |
| SCHEMBL12830369 | 0.72 | TDP1 (0.49) | MAPK1PTGESALOX5MMP1MMP7 | |
| SCHEMBL10516417 | 0.70 | MMP13 (0.40) | ALDH1A1HCRTR2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9068137-B2 | Water-mixed metal working fluids containing ether pyrrolidone carboxylic acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-06-30 | — | — | US | disclosed |
| US-8759264-B2 | Water-based hydraulic fluids comprising dithio-di(aryl carbolic acids) | CLARIENT FINANCE (BVI) LIMITED (VG) | 2014-06-24 | — | — | US | disclosed |
| US-20120088706-A1 | WATER-MIXED METAL WORKING FLUIDS CONTAINING ETHER PYRROLIDONE CARBOXYLIC ACIDS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | disclosed |
| US-20120088705-A1 | POLYALKYLENE GLYCOL-BASED ETHER PYRROLIDONE CARBOXYLIC ACIDS, AND CONCENTRATES FOR THE PRODUCTION OF SYNTHETIC COOLING LUBRICANTS CONTAINING THE SAME | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | disclosed |
| US-20120040875-A1 | Water-Based Hydraulic Fluids Comprising Dithio-Di(Aryl Carbolic Acids) | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088705-A1 | POLYALKYLENE GLYCOL-BASED ETHER PYRROLIDONE CARBOXYLIC ACIDS, AND CONCENTRATES FOR THE PRODUCTION OF SYNTHETIC COOLING LUBRICANTS CONTAINING THE SAME | F12, ADH1A, ADH1C | ALDH1A1 241/4885HCRTR2 865/4885ADAMTS5 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.