SCHEMBL216185

SCHEMBL216185

O=S(=O)(Nc1ccccc1)C(F)(F)F

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.62
CA2 P00918 6/20 0.60
PTPN11 Q06124 1/20 0.60
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
PTGS1 P23219 3/20 0.54
PTGS2 P35354 3/20 0.54
CA1 P00915 3/20 0.53
KEAP1 Q14145 2/20 0.52
IL1RN P18510 1/20 0.50
ERAP1 Q9NZ08 1/20 0.50
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM1A O60341 1/20 0.44
HSPD1 P10809 1/20 0.43
HSPE1 P61604 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1976973 0.98 PTPN1 (0.60) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL28665290 0.98 PTPN1 (0.60) PTPN1CA2PTPN11MAPK1SMN1; SMN2
Trifluoromethanesulfonamide SCHEMBL4288876 0.92 CA2 (0.62) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL19042259 0.87 CA2 (0.49) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL17266478 0.86 PTPN1 (0.49) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL18048059 0.84 PTPN1 (0.51) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL6001500 0.83 PTPN1 (0.86) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL28027003 0.83 PTPN1 (0.54) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL14033372 0.82 LMNA (0.59) PTPN1CA2PTPN11MAPK1SMN1; SMN2
SCHEMBL4972432 0.81 PTGS1 (0.70) CA2PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11707538-B2 Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides WASHINGTON UNIVERSITY (US) 2023-07-25 US claimed
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride WASHINGTON UNIVERSITY (US) 2022-02-08 US claimed
US-20210236659-A1 METHODS AND DEVICES TO GENERATE [F-18]TRIFLYL FLUORIDE AND OTHER [F-18] SULFONYL FLUORIDES WASHINGTON UNIVERSITY (US) 2021-08-05 US claimed
CN-112375016-A Preparation process of N-phenyl bis (trifluoromethanesulfonimide) 江西国化实业有限公司 2021-02-19 CN claimed
CN-111269152-A Preparation method of N-phenyl bis (trifluoromethanesulfonyl) imide 江苏笃行致远新材料科技有限公司 2020-06-12 CN claimed
US-20150191437-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS ABBVIE INC. (US) 2015-07-09 US claimed
US-20130224149-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS ABBVIE INC. (US) 2013-08-29 US claimed
JP-4644254-B2 2011-03-02 JP claimed
CN-100484926-C azo metal chelate and preparation method thereof SHANGHAI INST OPTICS & FINE ME (CN) 2009-05-06 CN claimed
EP-2004595-A1 N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES Schering-Plough Ltd. (CH) 2008-12-24 EP claimed
EP-0149423-B1 PROCESS FOR THE PROTECTION OF KERATINIC MATERIAL AGAINST THE ATTACK OF KERATIN EATING INSECTS AND PHENOXYTRIFLUOROMETHANE SULFONANILIDES CIBA-GEIGY AG (CH) 1987-10-28 EP claimed
US-4659371-A NONPHYTOTOXIC TO COTTON KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-04-21 US claimed
US-4500608-A ACRYLIC ESTER, HALOGEN INITIATOR, SECOND INITIATOR, AND POLYMERIZATION INHIBITOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-02-19 US claimed
EP-0051365-B1 ANAEROBICALLY CURING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-09 EP claimed
EP-0051366-B1 TWO-PART, ANAEROBICALLY-CURING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-18 EP claimed
US-4452955-A TWO PARTS-UNSATURATED CARBOXYL MONOMER ACCELERATOR AND POLYMERIZATION INHIBITOR, AND REACTION PRODUCT OF ALDEHYDE AND AMINE MINNESOTA MINING & MANUFACTURING COMPANY (US) 1984-06-05 US claimed
US-4373077-A Anaerobically curing compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-02-08 US claimed
EP-0051365-A1 Anaerobically curing compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-05-12 EP claimed
EP-0051366-A1 Two-part, anaerobically-curing compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-05-12 EP claimed
US-4316000-A PERFLUOROALKYLSULFONANILIDE INITIATOR AND A TERTIARY OR SECONDARY AROMATIC AMINE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130224149-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS HAVCR2, RNASE1, MAVS PTPN1 2810/4885CA2 4346/4885PTPN11 2801/4885
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride STX18, GPR119, SLC5A1 PTPN1 2929/4885CA2 818/4885PTPN11 3003/4885
US-11707538-B2 Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides STX18, PFAS, FLI1 PTPN1 3369/4885CA2 1542/4885PTPN11 2994/4885
US-20210236659-A1 METHODS AND DEVICES TO GENERATE [F-18]TRIFLYL FLUORIDE AND OTHER [F-18] SULFONYL FLUORIDES STX18, PFAS, FLI1 PTPN1 3369/4885CA2 1542/4885PTPN11 2994/4885
US-20150191437-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS HAVCR2, RNASE1, MAVS PTPN1 2810/4885CA2 4346/4885PTPN11 2801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.