Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482251 | 0.88 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1ARFFAR1DRD2 | |
| SCHEMBL6475312 | 0.86 | CA2 (0.40) | CYSLTR2CYSLTR1CA2HTR6PTGS1 | |
| SCHEMBL6475717 | 0.85 | CA2 (0.43) | PTPN1CYSLTR2CYSLTR1CA2HTR6 | |
| SCHEMBL6474786 | 0.85 | LTB4R (0.41) | PTPN1CYSLTR2CYSLTR1CA2PTGS1 | |
| SCHEMBL6475351 | 0.83 | IKBKB (0.46) | CYSLTR2CYSLTR1CA2PTGS1PTGS2 | |
| SCHEMBL6479679 | 0.83 | KDM1A (0.42) | CYSLTR2CYSLTR1CA2PTGS1PTGS2 | |
| SCHEMBL6483863 | 0.83 | PPARA (0.47) | CYSLTR2CYSLTR1CA2PTGS1PTGS2 | |
| SCHEMBL6482520 | 0.83 | KIF11 (0.46) | CYSLTR2CYSLTR1CA2AR | |
| SCHEMBL6482540 | 0.81 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1CA2FFAR1PTGS1 | |
| SCHEMBL6474092 | 0.81 | PPARA (0.41) | CYSLTR2CYSLTR1CA2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930131-B2 | Aryl substituted 3-ethoxy phenyl trifluoromethane sulfonamides for the treatment of non-insulin dependent diabetes mellitus (NIDDM) | WYETH (US) | 2005-08-16 | — | — | US | disclosed |
| US-20030203941-A1 | Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus | WYETH (US) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203941-A1 | Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus | GPR119, INSR, SLC5A1 | PTPN1 54/4885CYSLTR2 4703/4885CYSLTR1 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.