SCHEMBL6001812

SCHEMBL6001812

CC(C)(C)OC(=O)N1CC=CC(C2(C#N)CCNCC2)=C1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.32
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590851 0.74 DRD2 (0.32) KDM1A
SCHEMBL6001814 0.70 GPR119 (0.31)
SCHEMBL25346836 0.67 KDM1A (0.33) KDM1A
SCHEMBL5492828 0.65 PREP (0.36) KDM1A
SCHEMBL16763581 0.64 ALDH1A1 (0.47)
SCHEMBL2811591 0.63 PLAT (0.37) KDM1A
SCHEMBL17376304 0.62 PLAT (0.36)
SCHEMBL17376240 0.62 PLAT (0.39)
SCHEMBL17113437 0.61 KDM1A (0.39) KDM1A
SCHEMBL651457 0.61 OPRM1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1694677-A1 SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS Syngenta Participations AG (CH) 2006-08-30 EP disclosed
WO-2005061500-A1 SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS SYNGENTA PARTICIPATIONS AG (CH) 2005-07-07 WO disclosed