Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753185 | 0.86 | TSHR (1.00) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL7265734 | 0.82 | KDM4E (0.78) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL7265745 | 0.82 | KDM4E (0.78) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL4613461 | 0.82 | NPSR1 (0.73) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL13388185 | 0.81 | KDM4E (0.77) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL13588884 | 0.80 | KDM4E (0.76) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL4397563 | 0.80 | KDM4E (0.76) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL4387714 | 0.80 | KDM4E (0.76) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL13588907 | 0.80 | KDM4E (0.76) | ALDH1A1TSHRHSD17B10NPSR1KDM4E | |
| SCHEMBL13588943 | 0.80 | NPSR1 (0.70) | ALDH1A1TSHRHSD17B10NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148242-B2 | N-formyl hydroxylamine compounds, compositions and methods of use | NOVARTIS AG (CH) | 2006-12-12 | — | — | US | disclosed |
| EP-1401828-A1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | Vicuron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030045479-A1 | Novel N-formyl hydroxylamine compounds, compositions and methods of use | VICURON HOLDINGS LLC | 2003-03-06 | — | — | US | disclosed |
| WO-2002102790-A1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | VICURON PHARMACEUTICALS INC. (US) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045479-A1 | Novel N-formyl hydroxylamine compounds, compositions and methods of use | PDF, HNMT, AADAC | ALDH1A1 2056/4885TSHR 3513/4885HSD17B10 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.