Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391278 | 0.91 | TSHR (0.83) | TSHRALDH1A1USP2HSD17B10NPSR1 | |
| SCHEMBL4381618 | 0.91 | TSHR (0.83) | TSHRALDH1A1USP2HSD17B10NPSR1 | |
| SCHEMBL6001948 | 0.86 | ALDH1A1 (0.75) | TSHRALDH1A1USP2HSD17B10NPSR1 | |
| SCHEMBL7265734 | 0.84 | KDM4E (0.78) | TSHRALDH1A1HSD17B10NPSR1KDM4E | |
| SCHEMBL7265745 | 0.84 | KDM4E (0.78) | TSHRALDH1A1HSD17B10NPSR1KDM4E | |
| SCHEMBL4613461 | 0.84 | NPSR1 (0.73) | TSHRALDH1A1HSD17B10NPSR1KDM4E | |
| SCHEMBL13388185 | 0.84 | KDM4E (0.77) | TSHRALDH1A1HSD17B10NPSR1KDM4E | |
| SCHEMBL13588884 | 0.83 | KDM4E (0.76) | TSHRALDH1A1HSD17B10NPSR1KDM4E | |
| SCHEMBL4397563 | 0.83 | KDM4E (0.76) | TSHRALDH1A1HSD17B10NPSR1KDM4E | |
| SCHEMBL4387714 | 0.83 | KDM4E (0.76) | TSHRALDH1A1HSD17B10NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148242-B2 | N-formyl hydroxylamine compounds, compositions and methods of use | NOVARTIS AG (CH) | 2006-12-12 | — | — | US | disclosed |
| EP-1401828-B1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | VICURON PHARM INC (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1401828-A1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | Vicuron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030045479-A1 | Novel N-formyl hydroxylamine compounds, compositions and methods of use | VICURON HOLDINGS LLC | 2003-03-06 | — | — | US | disclosed |
| WO-2002102790-A1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | VICURON PHARMACEUTICALS INC. (US) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045479-A1 | Novel N-formyl hydroxylamine compounds, compositions and methods of use | PDF, HNMT, AADAC | TSHR 3513/4885ALDH1A1 2056/4885USP2 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.