Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002662 | 0.84 | MCL1 (0.41) | MAPTXDHMCL1 | |
| SCHEMBL6002969 | 0.83 | GPBAR1 (0.39) | MAPT | |
| SCHEMBL17625952 | 0.78 | NQO1 (0.47) | MAPTXDH | |
| SCHEMBL1317405 | 0.76 | NPC1 (0.46) | MAPT | |
| SCHEMBL6003637 | 0.76 | CYP2D6 (0.53) | MAPTXDH | |
| SCHEMBL6002967 | 0.74 | MCHR1 (0.38) | — | |
| SCHEMBL122883 | 0.73 | ACACB (0.45) | MAPTACACBHDAC1HDAC2HDAC8 | |
| SCHEMBL27554388 | 0.73 | METAP2 (0.47) | MAPT | |
| SCHEMBL27540440 | 0.72 | XDH (0.44) | MAPTXDH | |
| SCHEMBL27577279 | 0.70 | NPC1 (0.46) | XDHMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |