Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644886 | 0.81 | HRH3 (0.46) | TP53SMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL27540440 | 0.81 | XDH (0.44) | LMNAMEN1KMT2AMAPTNFKB1 | |
| SCHEMBL1119940 | 0.79 | METAP2 (0.42) | METAP2ALPLNISCHRAB9ASMN1; SMN2 | |
| SCHEMBL27584325 | 0.77 | ALDH1A1 (0.40) | TP53RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27584582 | 0.75 | METAP2 (0.42) | METAP2RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL1202001 | 0.75 | NOTUM (0.42) | METAP2CA12ALPLRAB9ASMN1; SMN2 | |
| SCHEMBL27606211 | 0.75 | METAP2 (0.42) | METAP2ALPLTP53RAB9ASMN1; SMN2 | |
| SCHEMBL4047707 | 0.75 | AKT1 (0.42) | METAP2RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27584597 | 0.74 | KIF11 (0.42) | TP53NISCHRAB9ANPC1LMNA | |
| SCHEMBL63014 | 0.74 | RAB9A (0.41) | METAP2TP53RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1284777-C | 5-membered heterocycles, preparation and use thereof as medicine | SOD CONSEILS RECH APPLIC (FR) | 2006-11-15 | — | — | CN | disclosed |
| CN-1535267-A | 5-membered heterocycles, preparation and use thereof as medicine | ��ѧ�о���Ӧ����ѯ��˾ | 2004-10-06 | — | — | CN | disclosed |