Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | PPM1A | P35813 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003055 | 0.85 | CYP1A2 (0.33) | MAPTCYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL2089506 | 0.81 | CYP1A2 (0.33) | CYP1A2CYP2A6MTNR1AMTNR1BCA2 | |
| SCHEMBL2091623 | 0.75 | CYP1A2 (0.37) | MAPTCYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL2091637 | 0.74 | MPO (0.32) | MPO | |
| SCHEMBL2091616 | 0.72 | CYP1A2 (0.38) | MAPTCYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL2090417 | 0.72 | CYP2A6 (0.38) | MAPTCYP1A2CYP2A6KDM4EALDH1A1 | |
| SCHEMBL16417587 | 0.67 | MAOA (0.38) | CYP2A6KDM4ECA2CYP19A1 | |
| SCHEMBL6003503 | 0.67 | MTNR1A (0.60) | MAPTCYP2A6MTNR1AMTNR1BCA2 | |
| SCHEMBL2097025 | 0.67 | CYP1A2 (0.33) | MAPTCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL12810668 | 0.66 | CRHR1 (0.40) | MAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |