Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002233 | 0.88 | ECE1 (0.43) | ECE1CNR2CNR1RORCALDH1A1 | |
| SCHEMBL6002242 | 0.86 | ECE1 (0.47) | ECE1CNR2CNR1RORCALDH1A1 | |
| SCHEMBL6002334 | 0.83 | SMN1; SMN2 (0.39) | ECE1ALDH1A1MAPK1SMN1; SMN2BRPF1 | |
| SCHEMBL6001987 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1SMN1; SMN2LMNABRPF1 | |
| SCHEMBL6001840 | 0.80 | CACNA1B (0.40) | ECE1ALDH1A1MAPK1SMN1; SMN2BRPF1 | |
| SCHEMBL6002221 | 0.80 | ECE1 (0.52) | ECE1CNR2CNR1RORCBRPF1 | |
| SCHEMBL6002268 | 0.71 | MAPK1 (0.38) | ECE1MAPK1SMN1; SMN2 | |
| SCHEMBL6001895 | 0.70 | POLB (0.47) | ECE1ALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL6001714 | 0.69 | MAPT (0.51) | MAPK1SMN1; SMN2LMNABRPF1HPGD | |
| SCHEMBL6002292 | 0.69 | SERPINE1 (0.48) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212296-B9 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1212296-B1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2005-11-09 | — | — | EP | claimed |