Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002268 | 0.86 | MAPK1 (0.38) | SERPINE1CCR2ECE1 | |
| SCHEMBL6001762 | 0.84 | SERPINE1 (0.67) | SERPINE1CCR2 | |
| SCHEMBL6002238 | 0.81 | CACNA1B (0.40) | SERPINE1ECE1 | |
| SCHEMBL6001817 | 0.80 | MAPK1 (0.43) | — | |
| SCHEMBL6002233 | 0.80 | ECE1 (0.43) | ECE1PPARG | |
| SCHEMBL9666902 | 0.75 | CCR2 (0.61) | CCR2 | |
| SCHEMBL6002334 | 0.75 | SMN1; SMN2 (0.39) | SERPINE1ECE1 | |
| SCHEMBL8697469 | 0.73 | CCR2 (0.63) | SERPINE1CCR2PPARG | |
| SCHEMBL6001828 | 0.73 | SMN1; SMN2 (0.43) | ECE1 | |
| SCHEMBL7076317 | 0.72 | PPARG (0.48) | CCR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212296-B9 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1212296-B1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2005-11-09 | — | — | EP | claimed |